ABUTH Pharma Journal (2023) · 2023
Olurishe et al.
Background: As part of efforts to address the problem of medication-related morbidity and mortality, MTM is evolving as a prominent pharmaceutical care service targeting patients with MCMCs aimed at optimizing therapeutic outcomes through appropriate/improved medication use and monitoring. Objectives: To evaluate the import of pharmacist led MTM intervention services on therapeutic outcomes in type 2 diabetic outpatients with other co-morbid medical conditions. Methods: A prospective, longitudinal and interventional study conducted among forty Type 2 Diabetic Mellitus out-patients with co-morbid medical conditions in a pilot MTM clinic at ABUTH, using structured questionnaires, and face to face interview. Patients were managed using the five core components of MTM (medication reviews, medication action plan, interventions/referral, and follow-up). Management outcomes, knowledge on disease, medication adherence, and selfcare were evaluated and analyzed using Pearson Chi-square. Results: There were significant decreases in 2-hours post prandial (p<0.05) and in medication adherence level (p=0.002) observed 3 months after MTM intervention. A decrease of 68%, 57% and 21% was recorded in the occurrence of drug interactions, drug identity problem and adverse drug reactions respectively. 5% of co-morbid obese and 9% of stage one hypertensive patients also moved to the class of overweight and pre-hypertension. Patient satisfaction assessment revealed that 90% were satisfied with the services received. Conclusion: MTM intervention services resulted in significant improvements in overall management outcomes, boosted patient confidence and satisfaction in health care services. We recommended the establishment of MTM unit as an integral part of the Department of Pharmaceutical Services in health-care facilities.
Volume: Vol. 1
Issue: No. 1
Pages: pp. 16–26
Year: 2023
Medication Therapy Management (MTM) is a pharmacist-led service that reviews a patient's full medication regimen to resolve drug therapy problems and improve outcomes. It is especially valuable for patients with multiple chronic conditions on polypharmacy, who face higher risks of drug interactions, non-adherence, and adverse drug reactions.
A pilot MTM clinic was run at ABUTH for 40 Type 2 diabetic outpatients with co-morbidities. Pharmacists applied the five core MTM elements — medication review, personal medication record, action plan, intervention/referral, and follow-up — with outcomes reassessed three months later.
Two-hour post-prandial glucose control and medication adherence both improved significantly (p<0.05 and p=0.002). Drug interactions, drug-identity problems, and adverse drug reactions fell by 68%, 57%, and 21% respectively, and 90% of patients reported satisfaction with the service.
Pharmacist-led MTM meaningfully improved diabetes management and patient confidence, supporting the case for a dedicated MTM unit within hospital pharmaceutical services.